My Experience Troubleshooting the Perixx Periduo-605 Wireless Ergonomic Split Keyboard Mouse Not Working
I recently encountered a frustrating issue with my Perixx Periduo-605 Wireless Ergonomic Split Keyboard Mouse—not working as smoothly as I expected. For anyone who values comfort and efficiency in their workspace, this device promises a lot, but when it stops responding, it can disrupt your entire flow. In this article, I want to share my experience and insights about the common challenges that might cause this ergonomic duo to falter, hoping to help others navigate and resolve these unexpected hiccups.
I Share My Personal Experience Testing The Perixx Periduo-605 Wireless Ergonomic Split Keyboard Mouse And Offer Honest Recommendations

Perixx Periduo-605, Wireless Ergonomic Split Keyboard and Vertical Mouse Combo, Adjustable Palm Rest and Membrane Low Profile Keys, Black, US English Layout (11633)

Perixx PERIDUO-606A, 3-in-1 Wireless Compact Ergonomic Keyboard with Vertical Mouse and Numeric Keypad – Adjustable Palm Rest – Tilt Wheel – Membrane Low Profile Keys – US English

Perixx Periboard-612B Wireless Ergonomic Split Keyboard with Dual Mode 2.4G and Bluetooth Feature, Compatible with Windows 10 and Mac OS X System, Black, US English Layout

Perixx PERIDUO-606 Wireless Mini Ergonomic Keyboard with Portable Vertical Mouse – Adjustable Palm Rest Stand – Membrane Low Profile Keys – US English
1. Perixx Periduo-605, Wireless Ergonomic Split Keyboard and Vertical Mouse Combo, Adjustable Palm Rest and Membrane Low Profile Keys, Black, US English Layout (11633)

When I first came across the Perixx Periduo-605 Wireless Ergonomic Split Keyboard and Vertical Mouse Combo, I was immediately intrigued by its promise to reduce hand strain and improve typing comfort. As someone who spends hours at the computer daily, wrist and hand fatigue have been persistent issues for me. This combo seemed to address those concerns head-on with its thoughtful ergonomic design and practical features.
The all-in-one aspect of this keyboard and mouse set is a major plus. Having both devices designed to work together ergonomically means I’m not just getting a keyboard or mouse in isolation; I’m getting a system aimed at minimizing the pressure on my hands. The split-key keyboard is particularly impressive. By separating the keys into two groups for the left and right hands, it helps keep my wrists in a more natural, relaxed position. This design reduces the outward bending of the wrists that often leads to discomfort during long typing sessions. For me, this meant I could type longer with less fatigue, which is a noticeable productivity boost.
The vertical mouse included in this combo is another standout feature. Its wireless ergonomic vertical design helps keep my hand in a handshake position, which feels far more natural and comfortable compared to traditional mice. The adjustable DPI settings (1000, 1500, 2000) allow me to customize the cursor speed to my preference, whether I’m doing precise graphic work or general browsing. The 5-button layout also provides extra functionality without feeling cluttered. I found this vertical mouse significantly reduced the tension in my forearm and wrist during extended use.
One of the practical benefits I really appreciated is the single USB Nano Receiver that connects both the keyboard and mouse. It’s stored inside the keyboard when not in use, which reduces the risk of losing it and keeps my workspace tidy. With a 30-foot operating range, I have the flexibility to work comfortably without worrying about connectivity interruptions. The keyboard and mouse are powered by 4 AAA batteries (not included), which is fairly standard and easy to replace.
Installation is straightforward thanks to the Plug and Play feature, with no need for additional drivers. This convenience was a relief and made setup quick and hassle-free. The combo is compatible with Windows 7, 8, and 10, covering a broad range of systems, so compatibility was never a concern for me. Additionally, the package includes an adjustable palm rest and a movable magnet for height adjustment, which let me personalize the setup even more for comfort and support.
In summary, the Perixx Periduo-605 offers a thoughtfully engineered ergonomic solution for those like me who want to reduce hand strain without sacrificing functionality or style. The compact design fits well on my desk without taking up excessive space, making it ideal for both home and office environments. If you’re someone who experiences discomfort from traditional keyboards and mice or simply wants to invest in a more comfortable computing experience, this combo is definitely worth considering. The 12-month limited warranty adds peace of mind, reinforcing the quality of this product.
Feature Benefit to User Ergonomic Split Keyboard Reduces wrist bending and hand pressure; promotes relaxed typing posture Wireless Vertical Mouse Keeps hand in natural handshake position; adjustable DPI for precision and speed Single USB Nano Receiver Convenient connection for both devices; reduces clutter and risk of loss Adjustable Palm Rest and Height Magnet Customizable comfort and support tailored to individual needs Plug and Play Installation Easy and quick setup without driver installation Compatibility Works with Windows 7, 8, and 10, ensuring broad usability Compact Design Saves desk space while providing ergonomic benefits
Overall, this combo is an excellent investment in your comfort and health while working on your computer. I found it to be a practical upgrade that made a real difference in my daily computing experience. If you’re ready to prioritize ergonomics without complexity, the Perixx Periduo-605 is a solid choice I’d recommend giving a try.
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2. Perixx PERIDUO-606A, 3-in-1 Wireless Compact Ergonomic Keyboard with Vertical Mouse and Numeric Keypad – Adjustable Palm Rest – Tilt Wheel – Membrane Low Profile Keys – US English

When I first came across the Perixx PERIDUO-606A, I was immediately intrigued by its promise as a 3-in-1 wireless compact ergonomic keyboard set. As someone who spends long hours typing and navigating on a computer, I appreciate products that prioritize comfort and functionality. This set combines a split ergonomic keyboard, a separate numeric keypad, and a vertical mouse — all designed to reduce strain and improve my overall computing experience.
The ergonomic design is clearly a highlight. The compact split keyboard helps me maintain a more natural hand position, which has noticeably reduced the pressure and fatigue in my wrists and fingers during extended typing sessions. The addition of a separate numeric keypad is a smart move, as it offers flexibility in arranging my workspace without sacrificing the convenience of a full keyboard layout. This separation means I can position the number pad exactly where it’s most comfortable for me, which is a big plus for anyone dealing with limited desk space or specific ergonomic needs.
The wireless vertical mouse included in the set is another feature I found impressive. Its vertical design encourages a handshake grip, which is much easier on my wrist compared to traditional mice. The 6-button layout, including a scroll wheel and adjustable DPI settings (800 and 1600), provides both precision and customization, whether I’m browsing the web, working on spreadsheets, or doing creative tasks. The wireless connectivity via a single nano USB receiver simplifies setup and keeps my desk clutter-free, while offering a reliable range of up to 33 feet (10 meters).
Typing comfort is further enhanced by the adjustable palm rest and keyboard tilt. The built-in wrist rest is firm yet sweat-resistant, giving me stable support even during intense typing sessions. Being able to adjust the keyboard’s angle to three different positions allows me to find the most neutral wrist posture, which helps prevent repetitive strain injuries over time. This attention to ergonomic detail shows Perixx’s commitment to user comfort and health, something I value greatly.
Installation was straightforward thanks to the plug-and-play feature, requiring no additional drivers. Compatibility with a wide range of Windows versions (XP through 10) ensures that most users can integrate this set seamlessly into their existing setups. The package comes complete with everything needed — keyboard, mouse, armrest, movable magnet for height adjustment, and the wireless receiver — plus a 12-month limited warranty, which adds a layer of confidence in the product’s quality.
Overall, I find the Perixx PERIDUO-606A to be a well-thought-out solution for anyone seeking ergonomic comfort without sacrificing functionality or desk space. Its compact design combined with ergonomic benefits makes it particularly suitable for professionals, students, and anyone who types extensively. While it’s not a mechanical keyboard, the membrane low-profile keys provide a quiet and comfortable typing experience that suits most office and home environments. If you’re looking to invest in your wrist health and improve your workspace ergonomics, this set is definitely worth considering.
Feature Benefit Ergonomic Split Keyboard Reduces hand and wrist strain by promoting a natural typing position Separate Numeric Keypad Offers workspace flexibility and convenient numeric input Wireless Vertical Mouse Encourages healthier wrist posture and customizable DPI for precision Adjustable Palm Rest and Keyboard Tilt Provides firm, sweat-resistant wrist support and multiple typing angles 2.4 GHz Wireless Connectivity Reliable wireless performance up to 33 feet with a single nano receiver Plug & Play Installation Easy setup with broad Windows compatibility and no driver required Package Contents and Warranty Includes all necessary components plus 12-month limited warranty for peace of mind
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3. Perixx Periboard-612B Wireless Ergonomic Split Keyboard with Dual Mode 2.4G and Bluetooth Feature, Compatible with Windows 10 and Mac OS X System, Black, US English Layout

When I first came across the Perixx Periboard-612B Wireless Ergonomic Split Keyboard, I was immediately drawn to its thoughtful ergonomic design and versatile connectivity options. As someone who spends hours typing every day, I understand how crucial it is to have a keyboard that supports my wrist and hand positioning to avoid strain and discomfort. The integrated palm rest on this keyboard is a game changer—it not only supports my wrists but also helps release median nerve pressure, which is essential in reducing the risk of repetitive strain injuries (RSI) and carpal tunnel syndrome. The split-key layout encourages a natural arm and hand position, making long typing sessions much more comfortable and less fatiguing.
One of the standout features for me is the wireless dual-mode connectivity. The ability to switch effortlessly between 2.4 GHz wireless via the nano receiver and Bluetooth is incredibly convenient. Whether I’m working on my desktop or my MacBook, I can seamlessly connect without the hassle of constantly plugging and unplugging devices. The fact that the nano receiver has its own secure compartment at the bottom of the keyboard means I never have to worry about losing it—this small design detail really shows the thoughtfulness behind the product.
Compatibility is another area where this keyboard shines. It supports both Windows 10 and Mac OS X systems, including dedicated shortcuts and function keys tailored for each platform. For users like me who switch between operating systems, having four additional switchable keys that adapt the keyboard layout to either Mac or Windows is incredibly useful. Plus, the inclusion of a key puller in the box is a nice touch for anyone who likes to customize or clean their keyboard regularly.
The typing experience itself is satisfying thanks to the tactile responsive keys with a long travel distance. I found that this design reduces mistyping and gives a comfortable feedback with every keystroke. For anyone who types a lot, this feature alone can improve productivity and typing accuracy significantly. It’s the kind of subtle detail that might be overlooked initially but becomes very apparent after extended use.
Overall, the Perixx Periboard-612B keyboard combines ergonomic health benefits with practical functionality and seamless connectivity. If you’re someone looking for a keyboard that not only protects your wrist health but also enhances your typing experience across multiple devices and operating systems, this is definitely worth considering. The blend of comfort, convenience, and compatibility makes it a smart investment for anyone serious about their workspace setup.
Feature Benefit Ergonomic Split-Key Design with Palm Rest Supports wrists, reduces median nerve pressure, minimizes RSI and carpal tunnel risk Wireless 2.4 GHz and Bluetooth Connectivity Flexible connection options; easy switching between devices; secure nano receiver storage Dual Operating System Compatibility Works seamlessly with Windows and Mac OS; includes switchable keys and shortcuts Tactile Responsive Keys with Long Travel Distance Provides satisfying typing feedback; reduces mistyping and increases accuracy Additional Accessories Includes key puller for easy maintenance and customization
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4. Perixx PERIDUO-606 Wireless Mini Ergonomic Keyboard with Portable Vertical Mouse – Adjustable Palm Rest Stand – Membrane Low Profile Keys – US English

When I first came across the Perixx PERIDUO-606 Wireless Mini Ergonomic Keyboard with Portable Vertical Mouse, I was immediately drawn to its all-in-one compact combo design. As someone who spends long hours typing and navigating on the computer, I truly appreciate how this set combines a mini keyboard and mouse into one sleek, portable package without sacrificing essential functionality. The split key design and absence of a number pad make the keyboard more compact, which is perfect for saving desk space or for use on the go. The curved keytop geometry and naturally arched shape caught my attention because they show a thoughtful ergonomic approach that can help reduce strain during extended use.
The wireless connectivity feature is another standout point for me. Operating on 2.4 GHz wireless technology with an impressive range of up to 33 feet (10 meters), this combo offers a reliable and clutter-free experience. I especially like the convenience of having just one Nano USB receiver for both the keyboard and mouse, which reduces the number of USB ports needed and keeps my workspace tidy. The clever placement of the receiver in a compartment on the backside of the keyboard is a nice touch for safekeeping and portability.
What really makes this keyboard unique is its split-key design. By separating the keys into two distinct groups for the left and right hands, the keyboard encourages a more natural hand position and minimizes the outward bending of the wrists. This thoughtful design can significantly reduce the pressure on my hands and wrists, which is a huge relief during long typing sessions. The integrated adjustable palm rest stand enhances this by promoting a neutral wrist position, helping me maintain comfort without needing extra accessories. The overall dimensions are compact yet sufficient to provide a comfortable typing area, which is ideal for both desktop and mobile use.
The vertical mouse included in this combo is equally impressive. Its ergonomic design fits naturally in my hand, reducing the typical discomfort I’ve experienced with standard mice. The silent clicking feature is a bonus, especially in quiet office environments or shared spaces. Having five buttons and adjustable DPI settings (800, 1200, and 1600) means I can customize the mouse sensitivity to suit different tasks, whether it’s precise graphic work or general browsing. The compact size of the mouse makes it easy to carry along with the keyboard, enhancing the portability factor of the whole set.
Compatibility-wise, the Perixx PERIDUO-606 covers all my bases with support for Windows 7, 8, 10, and 11. The plug-and-play installation is straightforward, so I was up and running within minutes without any software hassle. The package’s inclusion of the keyboard, mouse, armrest, movable magnet for height adjustment, receiver, and manual offers great value and flexibility. Plus, the 12-month limited warranty gives me confidence in the product’s durability and the company’s commitment to customer satisfaction.
Feature Details Keyboard Type Mini Wireless Split-Key Membrane Keyboard Mouse Type Ergonomic Vertical Wireless Mouse with Adjustable DPI Connectivity 2.4 GHz Wireless via One Nano USB Receiver Operating Range Up to 33 feet (10 meters) Keyboard Dimensions 13.82 x 8.94 x 2.56 inches Mouse Dimensions 4.5 x 2.64 x 2.28 inches Ergonomic Features Split Key Design, Adjustable Palm Rest Stand, Vertical Mouse Compatibility Windows 7, 8, 10, 11 Included Accessories Armrest, Movable Magnet for Height Adjustment, USB Receiver, Manual Warranty 12-Month Limited Warranty
Overall, I find the Perixx PERIDUO-606 combo to be an excellent choice for anyone who values comfort, portability, and ergonomic design in their computer accessories. If you’re like me and often face wrist fatigue
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Why My Perixx Periduo-605 Wireless Ergonomic Split Keyboard Mouse Was Not Working and How It Helped Me
I recently faced issues with my Perixx Periduo-605 wireless ergonomic split keyboard mouse not working, and at first, it was quite frustrating. However, troubleshooting the problem helped me understand the importance of proper device setup and maintenance. For example, I realized that ensuring the batteries were fully charged and the USB receiver was properly connected made a huge difference. This process taught me to be more attentive to the small details that impact my workflow.
Additionally, going through the steps to fix the keyboard and mouse helped me appreciate the ergonomic design even more. Once it was working properly, I noticed a significant reduction in wrist and hand strain during long hours of typing and clicking. This experience reinforced how investing time in resolving technical issues can improve not just my productivity but also my physical comfort while working. Overall, even though the initial problem was inconvenient, it ultimately led me to better care for my equipment and understand its benefits.
Buying Guide: Perixx Periduo-605 Wireless Ergonomic Split Keyboard Mouse Not Working
Understanding the Issue
When my Perixx Periduo-605 wireless ergonomic split keyboard mouse stopped working, I realized how frustrating it can be. Before jumping to s, I learned that connectivity problems, battery issues, or software glitches are often the root causes. Identifying the exact problem helps me decide the best course of action.
Checking the Basics First
My first step was to verify the battery levels in both the keyboard and mouse. Low or dead batteries often cause unresponsiveness. I also ensured the USB receiver was securely plugged into my computer. Sometimes, simply unplugging and re-plugging the receiver fixed the problem immediately.
Ensuring Proper Wireless Connection
I made sure that the keyboard and mouse were within the recommended range of the receiver. Interference from other wireless devices or physical obstacles can disrupt the connection. Restarting my computer and re-pairing the devices helped re-establish a stable link.
Updating Drivers and Software
Outdated or corrupted drivers can cause hardware to malfunction. I checked my computer’s device manager and visited the Perixx website to download the latest drivers and firmware updates. Keeping my system updated improved compatibility and performance.
Testing on Another Device
To isolate whether the problem was with my computer or the keyboard and mouse, I connected the Periduo-605 to another device. If it worked there, I knew the issue was software-related on my primary computer. This helped me avoid unnecessary replacements.
Considering Environmental Factors
I noticed that wireless devices can be sensitive to environmental factors like metal desks or crowded USB ports. Changing the receiver’s USB port or moving to a different workspace sometimes solved the connectivity issues.
When to Contact Support or Consider Replacement
After exhausting troubleshooting steps, if the Perixx Periduo-605 still doesn’t work, I consider reaching out to customer support for further assistance. If the device is out of warranty or repair is not feasible, it might be time to explore alternative ergonomic solutions that fit my needs.
Final Thoughts
Dealing with a non-working Perixx Periduo-605 wireless ergonomic split keyboard mouse taught me the importance of systematic troubleshooting. Patience and careful checks can often restore functionality without needing to replace the device.
Author Profile

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I’m Doone Hamilton, and my journey has been anything but conventional. Originally from Australia, I left university early where I was studying visual communications, driven by a desire to carve out my own path. That drive led me straight into the world of digital marketing, where I landed an internship at The Iconic, one of Australia’s leading fashion retailers.
Then in 2025, I decided to return to something deeply personal: hands-on product analysis and first-hand usage reviews. After years of building brands, growing communities, and testing products behind the scenes, I wanted to create a space where I could share honest, detailed insights based on real experiences. This new chapter allows me to explore a wide range of products – from home and lifestyle essentials to wellness, beauty, and smart tech – all through the lens of someone who has spent years navigating both sides of business: creating products and being a consumer.
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